COVID-19 and kidney involvement: pathophysiological approach
DOI:
https://doi.org/10.62486/agmu202495Keywords:
COVID-19, Kidney, Renal diseaseAbstract
Introduction: Due to the great threat posed by COVID-19, the scientific community must have evidence of kidney damage in patients affected by this disease, which would make it possible to carry out actions aimed at its prevention and early detection.
Objectives: deepen knowledge about COVID-19 and its impact on the kidney.
Methods: a bibliographic review on COVID-19 and kidney was carried out, in research published in Spanish and English, in the PubMed, Scielo, and Dialnet databases. All documents published in the last five years (2019-2023) were selected, which included the keywords: COVID-19, kidney, kidney disease.
Conclusions: within the systemic involvement caused by COVID-19, the kidney plays a predominant role in its pathophysiology and as a target organ. Kidney disease is in itself a risk factor for morbidity and mortality and acute kidney failure worsens the prognosis; Hence, it is necessary to delve deeper into these topics every day to direct novel diagnostic and therapeutic strategies
References
Vargas JG, Ávila N, Hurtado D, Cárdenas-Roldán J, Peña D, Ortiz G. Lesión Renal Aguda en COVID-19: puesta al día y revisión de la literatura, Acta Colombiana Cuidados Intensivos, Elsevier,2020, 30;(20) 1-11. Disponible en: https://doi.org/10.1016/j.acci.2020.10.004 DOI: https://doi.org/10.1016/j.acci.2020.10.004
González Milán ZC, Alarcón González R, Escalona González SO. Daño renal en pacientes con COVID-19. Rev. Cub. Inv. Biomédicas. 2021 [acceso: 02/05/2021];40(2):e808. Disponible en: http://www.revibiomedica.sld.cu/index.php/ibi/article/view/808
Hidalgo-Blanco MÁ, Andreu-Periz D, Moreno-Arroyo MC. COVID-19 en el enfermo renal. Revisión breve. Enferm Nefrol [Internet]. 2020 Jun [citado 2023 Ago 26] ; 23( 2 ): 122-131. Disponible en: http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S2254-28842020000200002&lng=es DOI: https://doi.org/10.37551/S2254-28842020013
Zarzosa SG, Lucas JH, Llorente B, Trascasa M, Molina R, Serrano C, et al. Acute renal failure in COVID-19 patients on mechanical ventilation. Rev Chil Anest. 2021; 49(6):867–73. DOI: https://doi.org/10.25237/revchilanestv49n06-12
Shetty AK. Mesenchymal Stem Cell Infusion Shows Promise for Combating Coronavirus (COVID-19) Induced Pneumonia. Aging and Disease. 2020;11(2):462-4. DOI: 10.14336/AD.2020.0301 DOI: https://doi.org/10.14336/AD.2020.0301
Singhal T. A Review of Coronavirus Disease-2019 (COVID-19). The Indian Journal of Pediatrics (April 2020) 87(4):281–286 https://doi.org/10.1007/s12098-020-03263-6 DOI: https://doi.org/10.1007/s12098-020-03263-6
Vaduganathan M, Vardeny O, Michel T, McMurray JJV, Pfeffer MA, Solomon SD. Renin-Angiotensin-Aldosterone System Inhibitors in Patients with Covid-19 N Engl J Med. 2020;382:1653-9. DOI: https://doi.org/10.1056/NEJMsr2005760
Diao B, Feng Z, Wang C. Human kidney is a target for novel severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2). Infection. 2020;12(1):2506. DOI: 10.1101/2020.03.04.20031120v2 DOI: https://doi.org/10.1038/s41467-021-22781-1
Soler MJ, Macia Heras M, Ortiz A, del Pino y Pino MD, Salgueira Lazo M. Impacto de la pandemia COVID-19 en los servicios de Nefrología españoles. Nefrología [Internet]. 2020; 40(6):579–84. Disponible en: https://doi.org/10.1016/j.nefro.2020.08.002 DOI: https://doi.org/10.1016/j.nefro.2020.08.002
Pincay Luna MY, & Alcocer Diaz S. (2023). Perfil renal asociado a mortalidad por Covid 19 en pacientes de la unidad de cuidados intensivos a nivel de Latinoamérica . Revista Científica Arbitrada Multidisciplinaria PENTACIENCIAS, 5(3), 112–123. https://doi.org/10.59169/pentaciencias.v5i3.524 DOI: https://doi.org/10.59169/pentaciencias.v5i3.524
Caicedo Mesa A, et al. Pandemia de COVID-19 y enfermedad renal: ¿Qué sabemos actualmente?. Rev. colom. nefrol. [online]. 2020, vol.7, suppl.2, pp.221-248. Epub May 10, 2021. ISSN 2500-5006. https://doi.org/10.22265/acnef.7.supl.2.438 DOI: https://doi.org/10.22265/acnef.7.Supl.2.438
Chu KH, Tsang WK, Tang CS, Lam MF, Lai FM, To KF, et al. Acute renal impairment in coronavirus-associated severe acute respiratory syndrome. Kidney Int 2005;67(2):698-705. Available from: https://doi.org/10.1111/j.1523-1755.2005.67130.x DOI: https://doi.org/10.1111/j.1523-1755.2005.67130.x
Xianghong Y, Renhua S, Dechang C. Diagnóstico y tratamiento de la nueva neumonía por coronavirus: no se puede ignorar la lesión renal aguda. Chin Med J (Engl) 2020. Available from: https://doi.org/10.3760/cma.j.cn112137-20200229-00520
Hernández-Rivera JCH, Silva-Rueda RI, Salazar-Mendoza M, Pazos-Pérez F, Pérez-López MJ, Bermúdez-Aceves L, et al. COVID-19 generalidades y enfermedad renal. Artículo de revisión. Gac Med Bilbao. 2021;118:143–159
Fragale G, Baña Matías T, Magenta M, Beitia V, Karl A, Cortés L, et al . Valor pronóstico del compromiso renal en COVID-19. Rev. nefrol. dial. traspl. [Internet]. 2022 Mar [citado 2023 Ago 25] ; 42( 1 ): 4-10. Disponible en: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S2346-85482022000100004&lng=es
Escalona-González S, González-Milán Z, Ricardo-Paez B. Enfermedad renal crónica como causa importante de mortalidad en pacientes con COVID-19 en Cuba. Revista Cubana de Medicina [Internet]. 2022 [citado 25 Ago 2023]; 61 Disponible en: https://revmedicina.sld.cu/index.php/med/article/view/2704
Ikizler T. COVID-19 y Unidades de Diálisis: ¿Qué sabemos ahora y qué debemos hacer? AJKD. 2020;76(1):1-3 DOI: 10.1053/j.ajkd.2020.03.008 DOI: https://doi.org/10.1053/j.ajkd.2020.03.008
Zhang F, Liang Y. The potential risk of kidney vulnerable to novel coronavirus 2019 infection. Am J Physiol Physiol 2020:ajprenal.00085.2020. Available from: https://doi.org/10.1152/ajprenal.00085.2020 DOI: https://doi.org/10.1152/ajprenal.00085.2020
Izzedine H, Jhaveri KD, Perazella MA. COVID-19 therapeutic options for patients with Kidney Disease. Kidney Int 2020;0. Available from: https://doi.org/10.1016/j.kint.2020.03.015 DOI: https://doi.org/10.1016/j.kint.2020.03.015
de Armas Gil Tomás, Herrera Oropesa Yeneisis, Barroso Cruz Jorge, Joseph Planas Harold Ricardo, Rey Torres Ailyn Bárbara, Fuentes Abreu Jorge et al . La COVID-19 en pacientes con enfermedad renal crónica en hemodiálisis. Rev Cub Med Mil [Internet]. 2021 Mar [citado 2023 Nov 02] ; 50( 1 ): e859. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0138-65572021000100010&lng=es
Coello Roberto D., Salgado Walter, Pazmiño Gomez Betty J., Vazquez Vanina, Veron Delma. La pandemia de COVID-19 y el riñón, Guayas, Ecuador. Rev. nefrol. dial. traspl. [Internet]. 2020 Dic [citado 2023 Nov 02] ; 40( 4 ): 279-294. Disponible en: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S2346-85482020000400279&lng=es
Flores Gavino Aldo, Espinoza Anchaygua Ricardo, Herrera-Añazco Percy, Rodriguez-Morales Alfonso J.. SARS-COV-2 y su efecto a nivel de tejido renal: Una revisión narrativa. Acta méd. Peru [Internet]. 2021 Ene [citado 2023 Nov 02] ; 38( 1 ): 53-57. Disponible en: http://www.scielo.org.pe/scielo.php?script=sci_arttext&pid=S1728-59172021000100053&lng=es. Epub 23-Mayo-2021. http://dx.doi.org/10.35663/amp.2021.381.1885 DOI: https://doi.org/10.35663/amp.2021.381.1885
Treviño-Becerra Alejandro, Grajales-García Dulce P., Feria Ramírez José A.. COVID 19 y enfermedad renal crónica. Gac. Méd. Méx [revista en la Internet]. 2022 Ago [citado 2023 Nov 03] ; 158( 4 ): 187-189. Disponible en: http://www.scielo.org.mx/scielo.php?script=sci_arttext&pid=S0016-38132022000400187&lng=es DOI: https://doi.org/10.24875/GMM.22000133
Published
Issue
Section
License
Copyright (c) 2024 Yangel Fuentes Milián, Patricia Prieto Milián (Author)

This work is licensed under a Creative Commons Attribution 4.0 International License.
The article is distributed under the Creative Commons Attribution 4.0 License. Unless otherwise stated, associated published material is distributed under the same licence.